Facilities for running simulations from ordinary
differential equation ('ODE') models, such as pharmacometrics and other
compartmental models. A compilation manager translates the ODE model
into C, compiles it, and dynamically loads the object code into R for
improved computational efficiency. An event table object facilitates
the specification of complex dosing regimens (optional) and sampling
schedules. NB: The use of this package requires both C and
Fortran compilers, for details on their use with R please see
Section 6.3, Appendix A, and Appendix D in the "R Administration and
Installation" manual. Also the code is mostly released under GPL. The
'VODE' and 'LSODA' are in the public domain. The information is available
in the inst/COPYRIGHTS.
| Version: |
4.1.1 |
| Depends: |
R (≥ 4.0.0) |
| Imports: |
PreciseSums (≥ 0.7), Rcpp (≥ 0.12.3), backports, cli (≥
2.0.0), checkmate, ggplot2 (≥ 3.4.0), inline, lotri (≥
1.0.2), magrittr, memoise, methods, rex, sys, tools, utils, dparser (≥ 1.3.1-12), rxode2ll (≥ 2.0.9), data.table (≥
1.12.4), qs (≥ 0.26.3) |
| LinkingTo: |
sitmo, lotri (≥ 1.0.0), PreciseSums (≥ 0.7), Rcpp, RcppArmadillo (≥ 0.9.300.2.0), BH, RcppParallel, RcppEigen (≥
0.3.3.9.2), StanHeaders (≥ 2.21.0.7), dparser (≥ 1.3.1-12) |
| Suggests: |
Matrix, DT, covr, crayon, curl, digest, dplyr (≥ 0.8.0), ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark, nlme, remotes, rlang, rmarkdown, scales, shiny, stringi, symengine, testthat, tidyr, usethis, vdiffr (≥ 1.0), withr, xgxr, pillar, tibble, units (≥ 0.6-0), rsconnect, devtools, patchwork, nlmixr2data, lifecycle, kableExtra, pmxTools, rootSolve |
| Published: |
2025-10-08 |
| DOI: |
10.32614/CRAN.package.rxode2 |
| Author: |
Matthew L. Fidler 
[aut, cre],
Wenping Wang [aut],
Alan Hindmarsh [ctb],
Arun Srinivasan [ctb],
Awad H. Al-Mohy [ctb],
Bill Denney [ctb],
Cleve Moler [ctb],
David Cooley [ctb],
Drew Schmidt [ctb],
Ernst Hairer [ctb],
Gabriel Staples [ctb],
Gerhard Wanner [ctb],
Gilbert Stewart [ctb],
Goro Fuji [ctb],
Hadley Wickham [ctb],
Igor Kushnir [ctb],
Jack Dongarra [ctb],
Jim Bunch [ctb],
Kevin Ushey [ctb],
Linda Petzold [ctb],
Martin Maechler [ctb],
Matt Dowle [ctb],
Matteo Fasiolo [ctb],
Melissa Hallow [aut],
Michel Lang [ctb],
Morwenn [ctb],
Nicholas J. Higham [ctb],
Omar Elashkar [ctb],
Richard Upton [ctb],
Roger B. Sidje [ctb],
Simon Frost [ctb],
Yu Feng [ctb],
Zufar Mulyukov [ctb] |
| Maintainer: |
Matthew L. Fidler <matthew.fidler at gmail.com> |
| BugReports: |
https://github.com/nlmixr2/rxode2/issues/ |
| License: |
GPL (≥ 3) |
| Copyright: |
see file COPYRIGHTS |
| URL: |
https://nlmixr2.github.io/rxode2/,
https://github.com/nlmixr2/rxode2/ |
| NeedsCompilation: |
yes |
| Language: |
en-US |
| Citation: |
rxode2 citation info |
| Materials: |
README, NEWS |
| In views: |
DifferentialEquations, HighPerformanceComputing, MixedModels, Pharmacokinetics |
| CRAN checks: |
rxode2 results |