nlmixr2auto: Automated Population Pharmacokinetic Modeling

Automated population pharmacokinetic modeling framework for data-driven initialisation, model evaluation, and metaheuristic optimization. Supports genetic algorithms, ant colony optimization, tabu search, and stepwise procedures for automated model selection and parameter estimation within the nlmixr2 ecosystem.

Version:	1.0.0
Depends:	R (≥ 4.1.0), nlmixr2data
Imports:	nlmixr2, nlmixr2est, nlmixr2autoinit, rxode2, dplyr, progressr, processx (> 3.8.0), withr, crayon
Published:	2026-02-06
DOI:	10.32614/CRAN.package.nlmixr2auto (may not be active yet)
Author:	Zhonghui Huang [aut, cre], Joseph Standing [ctb], Matthew Fidler [ctb], Frank Kloprogge [ctb]
Maintainer:	Zhonghui Huang <huangzhonghui22 at gmail.com>
BugReports:	https://github.com/ucl-pharmacometrics/nlmixr2auto/issues
License:	GPL (≥ 3)
URL:	https://github.com/ucl-pharmacometrics/nlmixr2auto
NeedsCompilation:	no
Language:	en-US
CRAN checks:	nlmixr2auto results

Documentation:

Reference manual:

nlmixr2auto.html , nlmixr2auto.pdf

Downloads:

Package source:	nlmixr2auto_1.0.0.tar.gz
Windows binaries:	r-devel: nlmixr2auto_1.0.0.zip, r-release: not available, r-oldrel: not available
macOS binaries:	r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): nlmixr2auto_1.0.0.tgz, r-oldrel (x86_64): nlmixr2auto_1.0.0.tgz

Linking:

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