Tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the 'limma' method <doi:10.1093/nar/gkv007>, interaction testing between sex and disease, pathway enrichment with 'clusterProfiler' <doi:10.1089/omi.2011.0118>, and gene regulatory network (GRN) construction and analysis using 'igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.
| Version: | 0.1.1 |
| Depends: | R (≥ 3.6) |
| Imports: | limma, igraph, edgeR, Seurat, SeuratObject, clusterProfiler, org.Hs.eg.db, ReactomePA, data.table, ggplot2, tidyr, grid, ggraph, dplyr, ggrepel, scales, Rcpp, methods |
| LinkingTo: | Rcpp |
| Suggests: | R.utils, DT, gridExtra, knitr, htmltools, kableExtra, rmarkdown, stringr |
| Published: | 2025-11-13 |
| DOI: | 10.32614/CRAN.package.XYomics (may not be active yet) |
| Author: | Enrico Glaab [aut, cre], Sophie Le Bars [aut], Mohamed Soudy [aut], Murodzhon Akhmedov [cph] |
| Maintainer: | Enrico Glaab <enrico.glaab at uni.lu> |
| License: | MIT + file LICENSE |
| Copyright: | see file COPYRIGHTS |
| NeedsCompilation: | yes |
| Materials: | README |
| CRAN checks: | XYomics results |
| Reference manual: | XYomics.html , XYomics.pdf |
| Vignettes: |
Bulk RNA-Seq Example (source, R code) Single Cell Example (source, R code) |
| Package source: | XYomics_0.1.1.tar.gz |
| Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available |
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