dtptite: Dose Transition Pathways for Time-to-Event Dose-Finding Designs
Implements the Dose Transition Pathways (DTP) look-ahead strategy
for time-to-event phase I dose-finding clinical trials with delayed or
pending toxicity outcomes. Provides a DTP decorator for the 'escalation'
framework, supporting both TITE-CRM (model-based) and TITE-BOIN
(model-assisted) base designs.
| Version: |
0.1.0 |
| Depends: |
R (≥ 4.1.0) |
| Imports: |
BOIN, dplyr, escalation (≥ 0.2.0), stats, tibble |
| Suggests: |
dfcrm, ggplot2, testthat (≥ 3.0.0), TITEgBOIN |
| Published: |
2026-10-21 |
| DOI: |
10.32614/CRAN.package.dtptite (may not be active yet) |
| Author: |
Xiaoran Lai [aut, cre],
The Institute of Cancer Research [cph],
National Institute for Health and Care Research [fnd] |
| Maintainer: |
Xiaoran Lai <xiaoran.lai at icr.ac.uk> |
| BugReports: |
https://github.com/ICR-EPAT/dtptite/issues |
| License: |
GPL (≥ 3) |
| URL: |
https://github.com/ICR-EPAT/dtptite |
| NeedsCompilation: |
no |
| Materials: |
NEWS |
| CRAN checks: |
dtptite results |
Documentation:
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