Implements the Regional Association Score (RAS) method for genome-wide association studies (GWAS). For each single nucleotide polymorphism (SNP), RAS quantifies the strength of association within its surrounding genomic region, arranges these regional scores along the chromosome into a signal profile, and applies changepoint detection to locate association regions, improving statistical power while controlling the false positive rate. The method is described in Jiang and Zhang (2025) <doi:10.1073/pnas.2419721122>.
| Version: | 1.0.3 |
| Imports: | grDevices, graphics, parallel, segmented, stats |
| Suggests: | testthat (≥ 3.0.0) |
| Published: | 2026-07-24 |
| DOI: | 10.32614/CRAN.package.RAS (may not be active yet) |
| Author: | Yiran Jiang [aut], Jiahe Jin [aut, cre], Heping Zhang [aut] |
| Maintainer: | Jiahe Jin <jiahe.jin at yale.edu> |
| BugReports: | https://github.com/hepingzhangyale/RAS/issues |
| License: | MIT + file LICENSE |
| URL: | https://github.com/hepingzhangyale/RAS |
| NeedsCompilation: | yes |
| Citation: | RAS citation info |
| Materials: | README, NEWS |
| CRAN checks: | RAS results |
| Reference manual: | RAS.html , RAS.pdf |
| Package source: | RAS_1.0.3.tar.gz |
| Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): RAS_1.0.3.tgz, r-oldrel (arm64): RAS_1.0.3.tgz, r-release (x86_64): RAS_1.0.3.tgz, r-oldrel (x86_64): RAS_1.0.3.tgz |
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